List of EC numbers (EC 4)

This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

EC 4.1: Carbon-Carbon Lyases

EC 4.1.1: Carboxy-Lyases

EC 4.1.2: Aldehyde-Lyases

EC 4.1.2.1: deleted, included in EC 4.1.3.16
EC 4.1.2.2: ketotetrose-phosphate aldolase
EC 4.1.2.3: deleted, was pentosealdolase.
EC 4.1.2.4: deoxyribose-phosphate aldolase
EC 4.1.2.5: threonine aldolase
EC 4.1.2.6: deleted entry, was allothreonine aldolase. Reaction is due to EC 2.1.2.1 glycine hydroxymethyltransferase. See also EC 4.1.2.49.
EC 4.1.2.7: deleted, included in EC 4.1.2.13
EC 4.1.2.8: indole-3-glycerol-phosphate lyase^[1]^[2]
EC 4.1.2.9: phosphoketolase
EC 4.1.2.10: mandelonitrile lyase
EC 4.1.2.11: hydroxymandelonitrile lyase
EC 4.1.2.12: 2-dehydropantoate aldolase
EC 4.1.2.13: fructose-bisphosphate aldolase
EC 4.1.2.14: 2-dehydro-3-deoxy-phosphogluconate aldolase
EC 4.1.2.15: now EC 2.5.1.54
EC 4.1.2.16: now EC 2.5.1.55
EC 4.1.2.17: L-fuculose-phosphate aldolase
EC 4.1.2.18: 2-dehydro-3-deoxy-L-pentonate aldolase
EC 4.1.2.19: rhamnulose-1-phosphate aldolase
EC 4.1.2.20: 2-dehydro-3-deoxyglucarate aldolase
EC 4.1.2.21: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
EC 4.1.2.22: fructose-6-phosphate phosphoketolase
EC 4.1.2.23: 3-deoxy-D-manno-octulosonate aldolase
EC 4.1.2.24: dimethylaniline-N-oxide aldolase
EC 4.1.2.25: dihydroneopterin aldolase
EC 4.1.2.26: phenylserine aldolase
EC 4.1.2.27: sphinganine-1-phosphate aldolase
EC 4.1.2.28: 2-dehydro-3-deoxy-D-pentonate aldolase
EC 4.1.2.29: 5-dehydro-2-deoxyphosphogluconate aldolase
EC 4.1.2.30: 17a-hydroxyprogesterone aldolase
EC 4.1.2.31: deleted, included in EC 4.1.3.16
EC 4.1.2.32: trimethylamine-oxide aldolase
EC 4.1.2.33: fucosterol-epoxide lyase
EC 4.1.2.34: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
EC 4.1.2.35: propioin synthase
EC 4.1.2.36: lactate aldolase
EC 4.1.2.37: hydroxynitrilase
EC 4.1.2.38: benzoin aldolase
EC 4.1.2.39: Deleted, same as EC 4.1.2.37
EC 4.1.2.40: tagatose-bisphosphate aldolase
EC 4.1.2.41: vanillin synthase
EC 4.1.2.42: D-threonine aldolase
EC 4.1.2.43: 3-hexulose-6-phosphate synthase
EC 4.1.2.44: benzoyl-CoA-dihydrodiol lyase
EC 4.1.2.45: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
EC 4.1.2.46: aliphatic (R)-hydroxynitrile lyase
EC 4.1.2.47: (S)-hydroxynitrile lyase
EC 4.1.2.48: low-specificity L-threonine aldolase
EC 4.1.2.49: L-allo-threonine aldolase
EC 4.1.2.50: 6-carboxytetrahydropterin synthase

EC 4.1.3: Oxo-Acid-Lyases

EC 4.1.3.1: isocitrate lyase
EC 4.1.3.2: now EC 2.3.3.9
EC 4.1.3.3: N-acetylneuraminate lyase
EC 4.1.3.4: hydroxymethylglutaryl-CoA lyase
EC 4.1.3.5: now EC 2.3.3.10
EC 4.1.3.6: citrate (pro-3S)-lyase
EC 4.1.3.7: now EC 2.3.3.1
EC 4.1.3.8: now EC 2.3.3.8
EC 4.1.3.9: now EC 2.3.3.11
EC 4.1.3.10: now EC 2.3.3.7
EC 4.1.3.11: now EC 2.3.3.12
EC 4.1.3.12: now EC 2.3.3.13
EC 4.1.3.13: oxalomalate lyase
EC 4.1.3.14: 3-hydroxyaspartate aldolase
EC 4.1.3.15: now EC 2.2.1.5
EC 4.1.3.16: 4-hydroxy-2-oxoglutarate aldolase
EC 4.1.3.17: 4-hydroxy-4-methyl-2-oxoglutarate aldolase
EC 4.1.3.18: now EC 2.2.1.6
EC 4.1.3.19: now EC 2.5.1.56
EC 4.1.3.20: now EC 2.5.1.57
EC 4.1.3.21: now EC 2.3.3.14
EC 4.1.3.22: citramalate lyase
EC 4.1.3.23: now EC 2.3.3.2
EC 4.1.3.24: malyl-CoA lyase
EC 4.1.3.25: citramalyl-CoA lyase
EC 4.1.3.26: 3-hydroxy-3-isohexenylglutaryl-CoA lyase
EC 4.1.3.27: anthranilate synthase
EC 4.1.3.28: now EC 2.3.3.3
EC 4.1.3.29: now EC 2.3.3.4
EC 4.1.3.30: methylisocitrate lyase
EC 4.1.3.31: now EC 2.3.3.5
EC 4.1.3.32: 2,3-dimethylmalate lyase
EC 4.1.3.33: now EC 2.3.3.6
EC 4.1.3.34: citryl-CoA lyase
EC 4.1.3.35: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
EC 4.1.3.36: naphthoate synthase
EC 4.1.3.37: now EC 2.2.1.7
EC 4.1.3.38: aminodeoxychorismate lyase
EC 4.1.3.39: 4-hydroxy-2-oxovalerate aldolase
EC 4.1.3.40: chorismate lyase
EC 4.1.3.41: 3-hydroxy-D-aspartate aldolase

EC 4.1.99: Other Carbon-Carbon Lyases

EC 4.2: Carbon-Oxygen Lyases

EC 4.2.1: Hydro-lyases

EC 4.2.2: Acting on Polysaccharides

EC 4.2.3: Acting on phosphates

EC 4.2.99: Other Carbon-Oxygen Lyases

EC 4.2.99.1: now EC 4.2.2.2
EC 4.2.99.2: now EC 4.2.3.1
EC 4.2.99.3: now EC 4.2.2.2
EC 4.2.99.4: now EC 4.2.2.3
EC 4.2.99.5: deleted
EC 4.2.99.6: deleted, included in EC 4.2.2.4 and EC 4.2.2.5
EC 4.2.99.7: now EC 4.2.3.2
EC 4.2.99.8: now EC 2.5.1.47
EC 4.2.99.9: now EC 2.5.1.48
EC 4.2.99.10: now EC 2.5.1.49
EC 4.2.99.11: now EC 4.2.3.3
EC 4.2.99.12: carboxymethyloxysuccinate lyase
EC 4.2.99.13: now EC 2.5.1.50
EC 4.2.99.14: now EC 2.5.1.51
EC 4.2.99.15: now EC 2.5.1.52
EC 4.2.99.16: now EC 2.5.1.53
EC 4.2.99.17: now EC 4.2.99.14
EC 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase
EC 4.2.99.19: transferred entry, now EC 4.4.1.23
EC 4.2.99.20: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
EC 4.2.99.21: isochorismate lyase

EC 4.3: Carbon-Nitrogen Lyases

EC 4.3.1: Ammonia-Lyases

EC 4.3.1.1: aspartate ammonia-lyase
EC 4.3.1.2: methylaspartate ammonia-lyase
EC 4.3.1.3: histidine ammonia-lyase
EC 4.3.1.4: formiminotetrahydrofolate cyclodeaminase
EC 4.3.1.5: Now divided into EC 4.3.1.23 (tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase)
EC 4.3.1.6: b-alanyl-CoA ammonia-lyase
EC 4.3.1.7: ethanolamine ammonia-lyase
EC 4.3.1.8: now EC 2.5.1.61
EC 4.3.1.9: glucosaminate ammonia-lyase
EC 4.3.1.10: serine-sulfate ammonia-lyase
EC 4.3.1.11: dihydroxyphenylalanine ammonia-lyase
EC 4.3.1.12: ornithine cyclodeaminase
EC 4.3.1.13: carbamoyl-serine ammonia-lyase
EC 4.3.1.14: 3-aminobutyryl-CoA ammonia-lyase
EC 4.3.1.15: diaminopropionate ammonia-lyase
EC 4.3.1.16: threo-3-hydroxyaspartate ammonia-lyase
EC 4.3.1.17: L-serine ammonia-lyase
EC 4.3.1.18: D-serine ammonia-lyase
EC 4.3.1.19: threonine ammonia-lyase
EC 4.3.1.20: erythro-3-hydroxyaspartate ammonia-lyase
EC 4.3.1.21: Identical to EC 4.3.1.9
EC 4.3.1.22: 3,4-dihydroxyphenylalanine reductive deaminase
EC 4.3.1.23: tyrosine ammonia-lyase
EC 4.3.1.24: phenylalanine ammonia-lyase
EC 4.3.1.25: phenylalanine/tyrosine ammonia-lyase
EC 4.3.1.26: chromopyrrolate synthase is now EC 1.21.3.9, dichlorochromopyrrolate synthase
EC 4.3.1.27: threo-3-hydroxy-D-aspartate ammonia-lyase
EC 4.3.1.28: L-lysine cyclodeaminase

EC 4.3.2: Amidine-Lyases

EC 4.3.99: Other Carbon-Nitrogen Lyases

EC 4.4: Carbon-Sulfur Lyases

EC 4.4.1.1: cystathionine g-lyase
EC 4.4.1.2: homocysteine desulfhydrase
EC 4.4.1.3: dimethylpropiothetin dethiomethylase
EC 4.4.1.4: alliin lyase
EC 4.4.1.5: lactoylglutathione lyase
EC 4.4.1.6: S-alkylcysteine lyase
EC 4.4.1.7: deleted, included in EC 2.5.1.18
EC 4.4.1.8: cystathionine b-lyase
EC 4.4.1.9: L-3-cyanoalanine synthase
EC 4.4.1.10: cysteine lyase
EC 4.4.1.11: methionine g-lyase
EC 4.4.1.12: deleted
EC 4.4.1.13: cysteine-S-conjugate b-lyase
EC 4.4.1.14: 1-aminocyclopropane-1-carboxylate synthase
EC 4.4.1.15: D-cysteine desulfhydrase
EC 4.4.1.16: selenocysteine lyase
EC 4.4.1.17: holocytochrome-c synthase
EC 4.4.1.18: now EC 1.8.3.5
EC 4.4.1.19: phosphosulfolactate synthase
EC 4.4.1.20: leukotriene-C4 synthase
EC 4.4.1.21: S-ribosylhomocysteine lyase
EC 4.4.1.22: S-(hydroxymethyl)glutathione synthase
EC 4.4.1.23: 2-hydroxypropyl-CoM lyase
EC 4.4.1.24: (2R)-sulfolactate sulfo-lyase
EC 4.4.1.25: L-cysteate sulfo-lyase
EC 4.4.1.26: olivetolic acid cyclase

EC 4.5: Carbon-Halide Lyases

EC 4.6: Phosphorus-Oxygen Lyases

References

↑ "Enzyme: 4.1.2.8". Kyoto Encyclopedia of Genes and Genomes. Retrieved 2017-04-07.
↑ European Bioinformatics Institute. "EC 4.1.2.8". Integrated relational Enzyme database. Retrieved 2017-04-07.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[1] "Enzyme: 4.1.2.8". Kyoto Encyclopedia of Genes and Genomes. Retrieved 2017-04-07.

[2] European Bioinformatics Institute. "EC 4.1.2.8". Integrated relational Enzyme database. Retrieved 2017-04-07.

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

Carbon-carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases	Acetoacetate decarboxylase Adenosylmethionine decarboxylase Arginine decarboxylase Aromatic L-amino acid decarboxylase Glutamate decarboxylase Histidine decarboxylase Lysine decarboxylase Malonyl-CoA decarboxylase Ornithine decarboxylase Oxaloacetate decarboxylase Phosphoenolpyruvate carboxykinase Phosphoenolpyruvate carboxylase Phosphoribosylaminoimidazole carboxylase Pyrophosphomevalonate decarboxylase Pyruvate decarboxylase RuBisCO Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase Uroporphyrinogen III decarboxylase
4.1.2: Aldehyde-lyases	Fructose-bisphosphate aldolase Aldolase A Aldolase B Aldolase C 2-hydroxyphytanoyl-CoA lyase Threonine aldolase
4.1.3: Oxo-acid-lyases	Isocitrate lyase 3-hydroxy-3-methylglutaryl-CoA lyase
4.1.99: Other	Tryptophanase Photolyase CPD lyase Spore photoproduct lyase

Carbon-oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

Carbon-nitrogen lyases (EC 4.3)
4.3.1: ammonia-lyases	Histidine ammonia-lyase Formiminotransferase cyclodeaminase Serine dehydratase Phenylalanine ammonia-lyase
4.3.2: amidine-lyases	Argininosuccinate lyase Adenylosuccinate lyase