Beta-santalene synthase

Beta-santalene synthase
Identifiers
EC number 4.2.3.83
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-santalene synthase (EC 4.2.3.83) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (-)-beta-santalene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (-)-beta-santalene + diphosphate

The enzyme synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate.

References

  1. Jones, C.G.; Moniodis, J.; Zulak, K.G.; Scaffidi, A.; Plummer, J.A.; Ghisalberti, E.L.; Barbour, E.L.; Bohlmann, J. (2011). "Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases". J. Biol. Chem. 286: 17445–17454. doi:10.1074/jbc.m111.231787. PMC 3093818. PMID 21454632.
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