Cyanide hydratase

cyanide hydratase
Identifiers
EC number 4.2.1.66
CAS number 37292-83-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a cyanide hydratase (EC 4.2.1.66) is an enzyme that catalyzes the chemical reaction

formamide cyanide + H2O

Hence, this enzyme has one substrate, formamide, and two products, cyanide and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase. This enzyme participates in cyanoamino acid metabolism.

References

    • Fry WE, Millar RL (1972). "Cyanide degradion by an enzyme from Stemphylium loti". Arch. Biochem. Biophys. 151 (2): 468&ndash, 74. doi:10.1016/0003-9861(72)90523-1. PMID 5065258.


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