Uracil-5-carboxylate decarboxylase

uracil-5-carboxylate decarboxylase
Identifiers
EC number 4.1.1.66
CAS number 59299-01-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a uracil-5-carboxylate decarboxylase (EC 4.1.1.66) is an enzyme that catalyzes the chemical reaction

uracil 5-carboxylate uracil + CO2

Hence, this enzyme has one substrate, uracil 5-carboxylate, and two products, uracil and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is uracil-5-carboxylate carboxy-lyase (uracil-forming). Other names in common use include uracil-5-carboxylic acid decarboxylase, and uracil-5-carboxylate carboxy-lyase.

References

    • Palmatier RD, McCroskey RP, Abbott MT (1970). "The enzymatic conversion of uracil 5-carboxylic acid to uracil and carbon dioxide". J. Biol. Chem. 245 (24): 6706&ndash, 10. PMID 5482775.
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