Lupan-3beta,20-diol synthase
| Lupan-3beta,20-diol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.128 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Lupan-3beta,20-diol synthase (EC 4.2.1.128, LUP1 (gene)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming).[1][2] This enzyme catalyses the following chemical reaction
- lupan-3beta,20-diol (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
The reaction occurs in the reverse direction.
References
- ↑ Segura, M.J.; Meyer, M.M.; Matsuda, S.P. (2000). "Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol". Org. Lett. 2: 2257–2259. doi:10.1021/ol006016b. PMID 10930257.
- ↑ Kushiro, T.; Hoshino, M.; Tsutsumi, T.; Kawai, K.; Shiro, M.; Shibuya, M.; Ebizuka, Y. (2006). "Stereochemical course in water addition during LUP1-catalyzed triterpene cyclization". Org. Lett. 8: 5589–5592. doi:10.1021/ol062310d. PMID 17107079.
External links
- Lupan-3beta,20-diol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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