Alpha-farnesene synthase

Alpha-farnesene synthase
Identifiers
EC number 4.2.3.46
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-farnesene synthase (EC 4.2.3.46, (E,E)-alpha-farnesene synthase, AFS1, MdAFS1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate lyase ((3E,6E)-alpha-farnesene-forming).[1][2][3] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (3E,6E)-alpha-farnesene + diphosphate

References

  1. Pechous, S.W.; Whitaker, B.D. (2004). "Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit". Planta. 219 (1): 84–94. doi:10.1007/s00425-003-1191-4. PMID 14740213.
  2. Green, S.; Squire, C.J.; Nieuwenhuizen, N.J.; Baker, E.N.; Laing, W. (2009). "Defining the potassium binding region in an apple terpene synthase". J. Biol. Chem. 284 (13): 8661–8669. doi:10.1074/jbc.m807140200. PMC 2659225. PMID 19181671.
  3. Nieuwenhuizen, N.J.; Wang, M.Y.; Matich, A.J.; Green, S.A.; Chen, X.; Yauk, Y.K.; Beuning, L.L.; Nagegowda, D.A.; Dudareva, N.; Atkinson, R.G. (2009). "Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)". J. Exp. Bot. 60 (11): 3203–3219. doi:10.1093/jxb/erp162. PMC 2718223. PMID 19516075.
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