3-hydroxypropionyl-CoA dehydratase

3-hydroxypropionyl-CoA dehydratase
Identifiers
EC number 4.2.1.116
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) is an enzyme with systematic name 3-hydroxypropionyl-CoA hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

3-hydroxypropanoyl-CoA acrylyl-CoA + H2O

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.

References

  1. Berg, I.A.; Kockelkorn, D.; Buckel, W.; Fuchs, G. (2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318: 1782–1786. doi:10.1126/science.1149976. PMID 18079405.
  2. Teufel, R.; Kung, J.W.; Kockelkorn, D.; Alber, B.E.; Fuchs, G. (2009). "3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales". J. Bacteriol. 191: 4572–4581. doi:10.1128/JB.00068-09. PMC 2704735. PMID 19429610.
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