5alpha-hydroxysteroid dehydratase
| 5-alpha-hydroxysteroid dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.62 | ||||||||
| CAS number | 9075-27-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 5alpha-hydroxysteroid dehydratase (EC 4.2.1.62) is an enzyme that catalyzes the chemical reaction
- 5alpha-ergosta-7,22-diene-3beta,5-diol ergosterol + H2O
Hence, this enzyme has one substrate, 5alpha-ergosta-7,22-diene-3beta,5-diol, and two products, ergosterol and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming). This enzyme is also called 5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase.
References
- Topham RW, Gaylor JL (1970). "Isolation and purification of a 5 alpha-hydroxysterol dehydrase of yeast". J. Biol. Chem. 245 (9): 2319–27. PMID 5442273.
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