Diaminobutyrate decarboxylase

Diaminobutyrate decarboxylase
Identifiers
EC number 4.1.1.86
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, a diaminobutyrate decarboxylase (EC 4.1.1.86) is an enzyme that catalyzes the chemical reaction

L-2,4-diaminobutanoate propane-1,3-diamine + CO2

Hence, this enzyme has one substrate, L-2,4-diaminobutanoate, and two products, propane-1,3-diamine and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming). Other names in common use include DABA DC, L-2,4-diaminobutyrate decarboxylase, and L-2,4-diaminobutanoate carboxy-lyase.

References

    • Yamamoto S, Tsuzaki Y, Tougou K, Shinoda S (1992). "Purification and characterization of L-2,4-diaminobutyrate decarboxylase from Acinetobacter calcoaceticus". J. Gen. Microbiol. 138 (7): 1461&ndash, 5. doi:10.1099/00221287-138-7-1461. PMID 1512577.
    • Ikai H, Yamamoto S (1994). "Cloning and expression in Escherichia coli of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii". FEMS Microbiol. Lett. 124 (2): 225&ndash, 8. doi:10.1111/j.1574-6968.1994.tb07288.x. PMID 7813892.
    • Ikai H, Yamamoto S (1997). "Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii". J. Bacteriol. 179 (16): 5118&ndash, 25. PMC 179370. PMID 9260954.


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