Beta-selinene cyclase

Beta-selinene cyclase
Identifiers
EC number 4.2.3.66
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Beta-selinene cyclase (EC 4.2.3.66) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (beta-selinene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate beta-selinene + diphosphate

Initial cyclization gives (+)-germacrene A in an enzyme bound form.

References

  1. Belingher, L.; Cartayrade, A.; Pauly, G.; Gleizes, M. (1992). "Partial purification and properties of the sesquiterpene β-selinene cyclase from Citrofortunella mitis". Plant Sci. 84: 129–136. doi:10.1016/0168-9452(92)90126-7.
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