(+)-beta-caryophyllene synthase

(+)-beta-caryophyllene synthase
Identifiers
EC number 4.2.3.89
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(+)-beta-caryophyllene synthase (EC 4.2.3.89, GcoA) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-beta-caryophyllene-forming).[1] This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate (+)-beta-caryophyllene + diphosphate

This enzyme also converts the (+)-beta-caryophyllene to (+)-caryolan-1-ol.

References

  1. Nakano C, Horinouchi S, Ohnishi Y (August 2011). "Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus". The Journal of Biological Chemistry. 286 (32): 27980–7. doi:10.1074/jbc.m111.265652. PMC 3151043. PMID 21693706.
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