(+)-germacrene D synthase

(+)-germacrene D synthase
Identifiers
EC number 4.2.3.77
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(+)-germacrene D synthase (EC 4.2.3.77) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-germacrene-D-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-germacrene D + diphosphate

This enzyme requires Mg2+, Mn2+, Ni2+ or Co2+.

References

  1. Picaud, S.; Olsson, M.E.; Brodelius, M.; Brodelius, P.E. (2006). "Cloning, expression, purification and characterization of recombinant (+)-germacrene D synthase from Zingiber officinale". Arch. Biochem. Biophys. 452: 17–28. doi:10.1016/j.abb.2006.06.007. PMID 16839518.
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