Valencene synthase

Valencene synthase
Identifiers
EC number 4.2.3.73
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Valencene synthase (EC 4.2.3.73) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-valencene + diphosphate

The recombinant enzyme from Vitis vinifera forms (+)-valencene and (-)-7-epi-alpha-selinene.

References

  1. Lucker, J.; Bowen, P.; Bohlmann, J. (2004). "Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries". Phytochemistry. 65: 2649–2659. doi:10.1016/j.phytochem.2004.08.017. PMID 15464152.
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