ZNF644

ZNF644
Identifiers
AliasesZNF644, BM-005, MYP21, NatF, ZEP-2, zinc finger protein 644
External IDsMGI: 1277212 HomoloGene: 12971 GeneCards: ZNF644
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p22.2Start90,915,298 bp[1]
End91,022,272 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

84146

52397

Ensembl

ENSG00000122482

ENSMUSG00000049606

UniProt

Q9H582

n/a

RefSeq (mRNA)

NM_016620
NM_032186
NM_201269

RefSeq (protein)

NP_057704
NP_115562
NP_958357

n/a

Location (UCSC)Chr 1: 90.92 – 91.02 MbChr 5: 106.62 – 106.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a protein that in humans is encoded by the ZNF644 gene.[5]

Clinical relevance

Mutations in the ZNF644 gene have been found in sporadic cases of high myopia.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000122482 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049606 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: zinc finger protein 644".
  6. ↑ Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLoS Genetics. 7 (6): e1002084. doi:10.1371/journal.pgen.1002084. PMC 3111487. PMID 21695231.

Further reading

  • Zabaneh D, Balding DJ (2010). "A genome-wide association study of the metabolic syndrome in Indian Asian men". PLoS ONE. 5 (8): e11961. doi:10.1371/journal.pone.0011961. PMC 2915922. PMID 20694148.
  • Mulligan P, Westbrook TF, Ottinger M, et al. (2008). "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation". Mol. Cell. 32 (5): 718–26. doi:10.1016/j.molcel.2008.10.025. PMID 19061646.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
  • Zhang QH, Ye M, Wu XY, et al. (2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
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