KLF7

KLF7
Identifiers
AliasesKLF7, UKLF, Kruppel-like factor 7 (ubiquitous), Kruppel like factor 7
External IDsMGI: 1935151 HomoloGene: 2751 GeneCards: KLF7
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q33.3Start207,074,137 bp[1]
End207,167,267 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8609

93691

Ensembl

ENSG00000118263

ENSMUSG00000025959

UniProt

O75840

Q99JB0

RefSeq (mRNA)

NM_001270942
NM_001270943
NM_001270944
NM_003709

NM_033563

RefSeq (protein)

NP_001257871
NP_001257872
NP_001257873
NP_003700

NP_291041

Location (UCSC)Chr 2: 207.07 – 207.17 MbChr 1: 64.03 – 64.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a protein which in humans is encoded by the KLF7 gene.[5][6]

This protein is a member of the Kruppel-like family of transcription factors.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000118263 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025959 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: KLF7 Kruppel-like factor 7 (ubiquitous)".
  6. ↑ Matsumoto N, Laub F, Aldabe R, Zhang W, Ramirez F, Yoshida T, Terada M (October 1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors". The Journal of Biological Chemistry. 273 (43): 28229–37. doi:10.1074/jbc.273.43.28229. PMID 9774444.
  7. ↑ Bieker JJ (September 2001). "Krüppel-like factors: three fingers in many pies". The Journal of Biological Chemistry. 276 (37): 34355–8. doi:10.1074/jbc.R100043200. PMID 11443140.

Further reading

  • Cho SY, Park PJ, Shin HJ, et al. (2007). "(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells". Am. J. Physiol. Endocrinol. Metab. 292 (4): E1166–72. doi:10.1152/ajpendo.00436.2006. PMID 17164435.
  • Kawamura Y, Tanaka Y, Kawamori R, Maeda S (2006). "Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line". Mol. Endocrinol. 20 (4): 844–56. doi:10.1210/me.2005-0138. PMID 16339272.
  • Kanazawa A, Kawamura Y, Sekine A, et al. (2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes". Diabetologia. 48 (7): 1315–22. doi:10.1007/s00125-005-1797-0. PMID 15937668.
  • Smaldone S, Laub F, Else C, et al. (2004). "Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity". Mol. Cell. Biol. 24 (3): 1058–69. doi:10.1128/MCB.24.3.1058-1069.2004. PMC 321422. PMID 14729953.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Suzuki S, Chuang LF, Doi RH, Chuang RY (2004). "Identification of opioid-regulated genes in human lymphocytic cells by differential display: upregulation of Krüppel-like factor 7 by morphine". Exp. Cell Res. 291 (2): 340–51. doi:10.1016/S0014-4827(03)00408-7. PMID 14644156.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Matsumoto N, Laub F, Aldabe R, et al. (1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors". J. Biol. Chem. 273 (43): 28229–37. doi:10.1074/jbc.273.43.28229. PMID 9774444.


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