IRX5

IRX5
Identifiers
Aliases	IRX5, HMMS, IRX-2a, IRXB2, iroquois homeobox 5
External IDs	GeneCards: IRX5
Gene location (Human)
Chr.	Chromosome 16 (human)[1]
End	54,934,485 bp[1]
Gene ontology
Molecular function	• sequence-specific DNA binding; • DNA binding; • vitamin D binding; • RNA polymerase II transcription factor activity, sequence-specific DNA binding;
Cellular component	• cell nucleus;
Biological process	• retinal bipolar neuron differentiation; • regulation of gene expression; • embryonic cranial skeleton morphogenesis; • regulation of transcription, DNA-templated; • gonad development; • cell development; • transcription, DNA-templated; • regulation of heart rate; • visual perception; • neuron maturation; • response to stimulus; • regulation of transcription from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	10265
	n/a
	ENSG00000176842
	n/a
	P78411
	n/a
	NM_001252197; NM_005853
	n/a
	NP_001239126; NP_005844
	n/a
	Wikidata
View/Edit Human

Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene.^[3]^[4]

Function

IRX5 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.^[3]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000176842 - Ensembl, May 2017
↑ "Human PubMed Reference:".
1 2 "Entrez Gene: iroquois homeobox 1".
↑ Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T (2001). "Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes". Cytogenet. Cell Genet. 92 (3–4): 320–5. doi:10.1159/000056921. PMID 11435706.

External links

IRX5 human gene location in the UCSC Genome Browser.
IRX5 human gene details in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000176842 - Ensembl, May 2017

[2] "Human PubMed Reference:".

[entrez-3] 1 2 "Entrez Gene: iroquois homeobox 1".

[pmid11435706-4] Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T (2001). "Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes". Cytogenet. Cell Genet. 92 (3–4): 320–5. doi:10.1159/000056921. PMID 11435706.

IRX5

Function

References

Further reading

External links