MKX

MKX
Identifiers
AliasesMKX, C10orf48, IFRX, IRXL1, mohawk homeobox
External IDsMGI: 2687286 HomoloGene: 72239 GeneCards: MKX
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10p12.1Start27,672,875 bp[1]
End27,746,060 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

283078

210719

Ensembl

ENSG00000150051

ENSMUSG00000061013

UniProt

Q8IYA7

Q8BIA3

RefSeq (mRNA)

NM_001242702
NM_173576

NM_177595

RefSeq (protein)

NP_001229631
NP_775847

NP_808263

Location (UCSC)Chr 10: 27.67 – 27.75 MbChr 18: 6.91 – 7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX (mohawk homeobox) gene.[5]

Function

MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000150051 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061013 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: mohawk homeobox".
  6. ↑ Anderson DM, Arredondo J, Hahn K, Valente G, Martin JF, Wilson-Rawls J, Rawls A (March 2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID 16408284.

Further reading

  • Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1994). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.
  • Weinmann A, Galle PR, Teufel A (2005). "In silico characterization of an Iroquois family-related homeodomain protein". Int. J. Mol. Med. 16 (3): 443–8. doi:10.3892/ijmm.16.3.443. PMID 16077953.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Anderson DM, Arredondo J, Hahn K, et al. (2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID 16408284.
  • Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell. Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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