FOXK1

FOXK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2A3S, 2D2W
Identifiers
Aliases	FOXK1, FOXK1L, forkhead box K1
External IDs	MGI: 1347488 HomoloGene: 82414 GeneCards: FOXK1
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	4,771,443 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	142,462,011 bp[2]
RNA expression pattern
	; ;
	More reference expression data
Gene ontology
Molecular function	• transcription factor activity, sequence-specific DNA binding; • DNA binding; • sequence-specific DNA binding; • RNA polymerase II regulatory region sequence-specific DNA binding; • protein binding; • RNA polymerase II transcription factor activity, sequence-specific DNA binding; • transcription regulatory region sequence-specific DNA binding; • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; • transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding;
Cellular component	• cell nucleus; • nucleoplasm; • cytoplasm;
Biological process	• regulation of transcription from RNA polymerase II promoter; • positive regulation of transcription, DNA-templated; • multicellular organism development; • muscle organ development; • negative regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • protein deubiquitination; • anatomical structure morphogenesis; • cell differentiation; • negative regulation of transcription from RNA polymerase II promoter; • positive regulation of transcription from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	221937
	17425
	ENSG00000164916
	ENSMUSG00000056493
	P85037
	P42128
	NM_001037165
	NM_010812; NM_199068
	NP_001032242
	NP_951031
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein K1 is a protein that in humans is encoded by the FOXK1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164916 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056493 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Katoh M, Katoh M (Jun 2004). "Identification and characterization of human FOXK1 gene in silico". Int J Mol Med. 14 (1): 127–32. doi:10.3892/ijmm.14.1.127. PMID 15202027.
↑ "Entrez Gene: FOXK1 forkhead box K1".

Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Tsai KL, Huang CY, Chang CH, et al. (2006). "Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins". J. Biol. Chem. 281 (25): 17400–9. doi:10.1074/jbc.M600478200. PMID 16624804.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Huang JT, Lee V (2005). "Identification and characterization of a novel human FOXK1 gene in silico". Int. J. Oncol. 25 (3): 751–7. doi:10.3892/ijo.25.3.751. PMID 15289879.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000164916 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056493 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[pmid15202027-5] Katoh M, Katoh M (Jun 2004). "Identification and characterization of human FOXK1 gene in silico". Int J Mol Med. 14 (1): 127–32. doi:10.3892/ijmm.14.1.127. PMID 15202027.

[entrez-6] "Entrez Gene: FOXK1 forkhead box K1".

FOXK1

References

Further reading