OR9A4

OR9A4
Identifiers
AliasesOR9A4, olfactory receptor family 9 subfamily A member 4
External IDsMGI: 3030294 HomoloGene: 64866 GeneCards: OR9A4
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q34Start141,916,399 bp[1]
End141,920,625 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

130075

258381

Ensembl

ENSG00000258083

ENSMUSG00000045514

UniProt

Q8NGU2

Q8VF31

RefSeq (mRNA)

NM_001001656

NM_146383

RefSeq (protein)

NP_001001656

NP_666495

Location (UCSC)Chr 7: 141.92 – 141.92 MbChr 6: 40.57 – 40.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 9A4 is a protein that in humans is encoded by the OR9A4 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000258083 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045514 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR9A4 olfactory receptor, family 9, subfamily A, member 4".

Further reading

  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.