OR2A14

OR2A14
Identifiers
AliasesOR2A14, OR2A14P, OR2A6, OST182, olfactory receptor family 2 subfamily A member 14
External IDsMGI: 3030278 HomoloGene: 88438 GeneCards: OR2A14
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q35Start144,123,176 bp[1]
End144,131,188 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

135941

258650

Ensembl

ENSG00000221938
ENSG00000284891

ENSMUSG00000073110

UniProt

Q96R47

Q8VFS6

RefSeq (mRNA)

NM_001001659

NM_146656

RefSeq (protein)

NP_001001659

NP_666867

Location (UCSC)Chr 7: 144.12 – 144.13 MbChr 6: 42.95 – 42.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2A14 is a protein that in humans is encoded by the OR2A14 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 ENSG00000284891 GRCh38: Ensembl release 89: ENSG00000221938, ENSG00000284891 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000073110 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR2A14 olfactory receptor, family 2, subfamily A, member 14".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.