OR52L1

OR52L1
Identifiers
AliasesOR52L1, OR11-50, olfactory receptor family 52 subfamily L member 1
External IDsMGI: 3030519 HomoloGene: 66455 GeneCards: OR52L1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start5,985,892 bp[1]
End5,986,985 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

338751

258160

Ensembl

ENSG00000183313

ENSMUSG00000047794

UniProt

Q8NGH7

n/a

RefSeq (mRNA)

NM_001005173

NM_001011857

RefSeq (protein)

NP_001005173

n/a

Location (UCSC)Chr 11: 5.99 – 5.99 MbChr 7: 105.18 – 105.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 52L1 is a protein that in humans is encoded by the OR52L1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000183313 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047794 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR52L1 olfactory receptor, family 52, subfamily L, member 1".

Further reading

  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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