OR5AS1

OR5AS1
Identifiers
AliasesOR5AS1, OR11-168, olfactory receptor family 5 subfamily AS member 1
External IDsMGI: 3030945 HomoloGene: 74238 GeneCards: OR5AS1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q12.1Start56,027,654 bp[1]
End56,038,191 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

219447

258586

Ensembl

ENSG00000181785

ENSMUSG00000075158

UniProt

Q8N127

Q7TR55

RefSeq (mRNA)

NM_001001921

NM_146593

RefSeq (protein)

NP_001001921

NP_666804

Location (UCSC)Chr 11: 56.03 – 56.04 MbChr 2: 87.15 – 87.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein–coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181785 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000075158 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR5AS1 olfactory receptor, family 5, subfamily AS, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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