OR1D5

OR1D5
Identifiers
AliasesOR1D5, C17orf2, OR17-2, OR17-30, OR17-31, OR1D4, olfactory receptor family 1 subfamily D member 5
External IDsHomoloGene: 105312 GeneCards: OR1D5
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17p13.3Start3,062,669 bp[1]
End3,063,607 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

8386

n/a

Ensembl

ENSG00000262628

n/a

UniProt

P58170

n/a

RefSeq (mRNA)

NM_014566

n/a

RefSeq (protein)

NP_055381

n/a

Location (UCSC)Chr 17: 3.06 – 3.06 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene.[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000262628 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334.
  4. 1 2 "Entrez Gene: OR1D5 olfactory receptor, family 1, subfamily D, member 5".

Further reading

  • Selbie LA, Townsend-Nicholson A, Iismaa TP, Shine J (1992). "Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences". Brain Res. Mol. Brain Res. 13 (1–2): 159–63. doi:10.1016/0169-328X(92)90057-I. PMID 1315913.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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