OR52B4

OR52B4
Identifiers
AliasesOR52B4, OR11-3, olfactory receptor family 52 subfamily B member 4 (gene/pseudogene)
External IDsMGI: 3030381 HomoloGene: 17493 GeneCards: OR52B4
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start4,367,263 bp[1]
End4,368,386 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

143496

259083

Ensembl

ENSG00000221996

ENSMUSG00000073979

UniProt

Q8NGK2

E9PXN3

RefSeq (mRNA)

NM_001005161

NM_147079

RefSeq (protein)

NP_001005161

NP_667290

Location (UCSC)Chr 11: 4.37 – 4.37 MbChr 7: 102.53 – 102.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 52B4 is a protein that in humans is encoded by the OR52B4 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000221996 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000073979 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR52B4 olfactory receptor, family 52, subfamily B, member 4".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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