OR6N1

OR6N1
Identifiers
AliasesOR6N1, OR1-22, olfactory receptor family 6 subfamily N member 1
External IDsMGI: 3030263 HomoloGene: 17366 GeneCards: OR6N1
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q23.1Start158,747,814 bp[1]
End158,772,195 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

128372

258717

Ensembl

ENSG00000197403

ENSMUSG00000049528

UniProt

Q8NGY5

n/a

RefSeq (mRNA)

NM_001005185

NM_146722

RefSeq (protein)

NP_001005185

n/a

Location (UCSC)Chr 1: 158.75 – 158.77 MbChr 1: 174.08 – 174.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 6N1 is a protein that in humans is encoded by the OR6N1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000197403 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049528 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR6N1 olfactory receptor, family 6, subfamily N, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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