OR2M3

OR2M3
Identifiers
AliasesOR2M3, OR1-54, OR2M3P, OR2M6, OST003, olfactory receptor family 2 subfamily M member 3
External IDsMGI: 3029998 HomoloGene: 51725 GeneCards: OR2M3
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q44Start248,197,265 bp[1]
End248,212,925 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

127062

258443

Ensembl

ENSG00000228198

ENSMUSG00000050742

UniProt

Q8NG83

Q8VF87

RefSeq (mRNA)

NM_001004689

NM_146451

RefSeq (protein)

NP_001004689

NP_666662

Location (UCSC)Chr 1: 248.2 – 248.21 MbChr 16: 19.28 – 19.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2M3 is a protein that in humans is encoded by the OR2M3 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000228198 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050742 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR2M3 olfactory receptor, family 2, subfamily M, member 3".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.