OR51E1

OR51E1
Identifiers
AliasesOR51E1, D-GPCR, DGPCR, GPR136, GPR164, OR51E1P, OR52A3P, POGR, PSGR2, olfactory receptor family 51 subfamily E member 1
External IDsMGI: 3030392 HomoloGene: 17503 GeneCards: OR51E1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start4,643,420 bp[1]
End4,655,488 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

143503

259097

Ensembl

ENSG00000180785

ENSMUSG00000070423

UniProt

Q8TCB6

Q8VGZ7

RefSeq (mRNA)

NM_152430

NM_147093

RefSeq (protein)

NP_689643

NP_667304

Location (UCSC)Chr 11: 4.64 – 4.66 MbChr 7: 102.7 – 102.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 51E1 is a protein that in humans is encoded by the OR51E1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000180785 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070423 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR51E1 olfactory receptor, family 51, subfamily E, member 1".

Further reading

  • Wang J, Weng J, Cai Y, et al. (2006). "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase". Prostate. 66 (8): 847–57. doi:10.1002/pros.20389. PMID 16491480.
  • Weng J, Wang J, Hu X, et al. (2007). "PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer". Int. J. Cancer. 118 (6): 1471–80. doi:10.1002/ijc.21527. PMID 16206286.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Weigle B, Fuessel S, Ebner R, et al. (2004). "D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate". Biochem. Biophys. Res. Commun. 322 (1): 239–49. doi:10.1016/j.bbrc.2004.07.106. PMID 15313197.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Vanti WB, Nguyen T, Cheng R, et al. (2003). "Novel human G-protein-coupled receptors". Biochem. Biophys. Res. Commun. 305 (1): 67–71. doi:10.1016/S0006-291X(03)00709-5. PMID 12732197.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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