OR5L1

OR5L1
Identifiers
AliasesOR5L1, OR11-151, OST262, olfactory receptor family 5 subfamily L member 1 (gene/pseudogene)
External IDsMGI: 3030991 HomoloGene: 17402 GeneCards: OR5L1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q12.1Start55,811,367 bp[1]
End55,812,476 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

219437

258846

Ensembl

ENSG00000279395

ENSMUSG00000075143

UniProt

Q8NGL2

A2AVC4

RefSeq (mRNA)

NM_001004738

NM_146849

RefSeq (protein)

NP_001004738

NP_667060

Location (UCSC)Chr 11: 55.81 – 55.81 MbChr 2: 87.96 – 87.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5L1 is a protein that in humans is encoded by the OR5L1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000279395 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000075143 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR5L1 olfactory receptor, family 5, subfamily L, member 1".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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