OR8G1

OR8G1
Identifiers
AliasesOR8G1, HSTPCR25, OR8G1P, TPCR25, olfactory receptor family 8 subfamily G member 1 (gene/pseudogene)
External IDsMGI: 3030801 HomoloGene: 115535 GeneCards: OR8G1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q24.2Start124,241,095 bp[1]
End124,254,364 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26494

258086

Ensembl

ENSG00000197849

ENSMUSG00000055820

UniProt

Q15617

Q7TRA6

RefSeq (mRNA)

NM_001002905

NM_001011826

RefSeq (protein)

NP_001002905

NP_001011826

Location (UCSC)Chr 11: 124.24 – 124.25 MbChr 9: 39.75 – 39.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 8G1 is a protein that in humans is encoded by the OR8G1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000197849 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055820 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
  6. 1 2 "Entrez Gene: OR8G1 olfactory receptor, family 8, subfamily G, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.