OR5A1

OR5A1
Identifiers
AliasesOR5A1, OR11-249, OR5A1P, OST181, olfactory receptor family 5 subfamily A member 1
External IDsMGI: 2153205 HomoloGene: 17342 GeneCards: OR5A1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q12.1Start59,436,469 bp[1]
End59,451,380 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

219982

258677

Ensembl

ENSG00000172320

ENSMUSG00000067522

UniProt

Q8NGJ0

Q8VFV2

RefSeq (mRNA)

NM_001004728

NM_146682

RefSeq (protein)

NP_001004728

NP_666893

Location (UCSC)Chr 11: 59.44 – 59.45 MbChr 19: 12.12 – 12.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5A1 is a protein that in humans is encoded by the OR5A1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000172320 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067522 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR5A1 olfactory receptor, family 5, subfamily A, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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