OR4F15

OR4F15
Identifiers
AliasesOR4F15, olfactory receptor family 4 subfamily F member 15
External IDsMGI: 3031143 HomoloGene: 74054 GeneCards: OR4F15
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q26.3Start101,812,202 bp[1]
End101,820,197 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

390649

258439

Ensembl

ENSG00000182854

ENSMUSG00000109528

UniProt

Q8NGB8

n/a

RefSeq (mRNA)

NM_001001674

NM_146447

RefSeq (protein)

NP_001001674

n/a

Location (UCSC)Chr 15: 101.81 – 101.82 MbChr 2: 111.98 – 111.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4F15 is a protein that in humans is encoded by the OR4F15 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000182854 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000109528 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR4F15 olfactory receptor, family 4, subfamily F, member 15".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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