OR2W3

OR2W3
Identifiers
AliasesOR2W3, OR2W3P, OR2W8P, OST718, olfactory receptor family 2 subfamily W member 3
External IDsMGI: 3030156 HomoloGene: 19876 GeneCards: OR2W3
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q44Start247,895,587 bp[1]
End247,896,531 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

343171

404346

Ensembl

ENSG00000238243

ENSMUSG00000063549

UniProt

Q7Z3T1

Q5NCC8

RefSeq (mRNA)

NM_001001957

NM_207693

RefSeq (protein)

NP_001001957

NP_997576

Location (UCSC)Chr 1: 247.9 – 247.9 MbChr 11: 58.66 – 58.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2W3 is a protein that in humans is encoded by the OR2W3 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000238243 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063549 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  6. 1 2 "Entrez Gene: OR2W3 olfactory receptor, family 2, subfamily W, member 3".

Further reading

  • Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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