OR4D10

OR4D10
Identifiers
AliasesOR4D10, OR11-251, OR4D10P, OST711, olfactory receptor family 4 subfamily D member 10
External IDsMGI: 3031258 HomoloGene: 82294 GeneCards: OR4D10
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q12.1Start59,473,315 bp[1]
End59,479,361 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

390197

258676

Ensembl

ENSG00000254466

ENSMUSG00000067528

UniProt

Q8NGI6

Q8VFV1

RefSeq (mRNA)

NM_001004705

NM_146681

RefSeq (protein)

NP_001004705

NP_666892

Location (UCSC)Chr 11: 59.47 – 59.48 MbChr 19: 12.06 – 12.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4D10 is a protein that in humans is encoded by the OR4D10 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000254466 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067528 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR4D10 olfactory receptor, family 4, subfamily D, member 10".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Gilad Y, Lancet D (2003). "Population differences in the human functional olfactory repertoire". Mol. Biol. Evol. 20 (3): 307–14. doi:10.1093/molbev/msg013. PMID 12644552.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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