OR2T1

OR2T1
Identifiers
AliasesOR2T1, OR1-25, olfactory receptor family 2 subfamily T member 1
External IDsMGI: 109304 HomoloGene: 74028 GeneCards: OR2T1
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q44Start248,403,048 bp[1]
End248,408,020 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26696

18330

Ensembl

ENSG00000275244
ENSG00000273508
ENSG00000175143

ENSMUSG00000072707

UniProt

O43869

n/a

RefSeq (mRNA)

NM_030904

NM_147027

RefSeq (protein)

NP_112166

n/a

Location (UCSC)Chr 1: 248.4 – 248.41 MbChr 14: 14.32 – 14.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2T1 is a protein that in humans is encoded by the OR2T1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 ENSG00000273508, ENSG00000175143 GRCh38: Ensembl release 89: ENSG00000275244, ENSG00000273508, ENSG00000175143 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000072707 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  6. 1 2 "Entrez Gene: OR2T1 olfactory receptor, family 2, subfamily T, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.