OR7C2

OR7C2
Identifiers
AliasesOR7C2, CIT-HSP-87M17, OR19-18, OR7C3, olfactory receptor family 7 subfamily C member 2
External IDsMGI: 3031190 HomoloGene: 71958 GeneCards: OR7C2
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19p13.12Start14,941,489 bp[1]
End14,942,448 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26658

258305

Ensembl

ENSG00000127529

ENSMUSG00000051190

UniProt

O60412

Q7TQU8

RefSeq (mRNA)

NM_012377

NM_146308

RefSeq (protein)

NP_036509

NP_666420

Location (UCSC)Chr 19: 14.94 – 14.94 MbChr 10: 78.85 – 78.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 7C2 is a protein that in humans is encoded by the OR7C2 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000127529 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051190 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR7C2 olfactory receptor, family 7, subfamily C, member 2".

Further reading

  • Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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