OR7C1

OR7C1
Identifiers
AliasesOR7C1, CIT-HSP-146E8, HSTPCR86P, OR19-5, OR7C4, TPCR86, olfactory receptor family 7 subfamily C member 1
External IDsMGI: 3031186 HomoloGene: 131141 GeneCards: OR7C1
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19p13.12Start14,789,260 bp[1]
End14,835,376 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26664

259074

Ensembl

ENSG00000127530

ENSMUSG00000046493

UniProt

O76099

n/a

RefSeq (mRNA)

NM_198944

NM_147071

RefSeq (protein)

NP_945182

n/a

Location (UCSC)Chr 19: 14.79 – 14.84 MbChr 10: 78.98 – 78.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 7C1 is a protein that in humans is encoded by the OR7C1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000127530 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046493 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR7C1 olfactory receptor, family 7, subfamily C, member 1".

Further reading

  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–246. doi:10.1006/geno.1996.4490. PMID 9119360.
  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome". Biochem. Biophys. Res. Commun. 237 (2): 283–287. doi:10.1006/bbrc.1997.7043. PMID 9268701.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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