OR52D1

OR52D1
Identifiers
AliasesOR52D1, OR11-43, olfactory receptor family 52 subfamily D member 1
External IDsMGI: 3030480 HomoloGene: 17481 GeneCards: OR52D1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start5,488,685 bp[1]
End5,489,749 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

390066

259058

Ensembl

ENSG00000181609

ENSMUSG00000073931

UniProt

Q9H346

Q8VGW2

RefSeq (mRNA)

NM_001005163

NM_147056

RefSeq (protein)

NP_001005163

NP_667267

Location (UCSC)Chr 11: 5.49 – 5.49 MbChr 7: 104.1 – 104.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 52D1 is a protein that in humans is encoded by the OR52D1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181609 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000073931 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR52D1 olfactory receptor, family 52, subfamily D, member 1".

Further reading

  • Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–5134. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430.
  • Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–14565. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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