OR11A1

OR11A1
Identifiers
AliasesOR11A1, 6M1-18, OR11A2, dJ994E9.6, hs6M1-18, olfactory receptor family 11 subfamily A member 1
External IDsMGI: 2177479 HomoloGene: 27189 GeneCards: OR11A1
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p22.1Start29,425,504 bp[1]
End29,457,071 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26531

258507

Ensembl

ENSMUSG00000064121

UniProt

Q9GZK7

Q8VFE3

RefSeq (mRNA)

NM_013937

NM_146514

RefSeq (protein)

NP_039225

NP_666725

Location (UCSC)Chr 6: 29.43 – 29.46 MbChr 17: 37.22 – 37.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 11A1 is a protein that in humans is encoded by the OR11A1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 ENSG00000230780, ENSG00000232289, ENSG00000234347, ENSG00000223898, ENSG00000206517, ENSG00000206472, ENSG00000204694 GRCh38: Ensembl release 89: ENSG00000237258, ENSG00000230780, ENSG00000232289, ENSG00000234347, ENSG00000223898, ENSG00000206517, ENSG00000206472, ENSG00000204694 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000064121 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR11A1 olfactory receptor, family 11, subfamily A, member 1".

Further reading

  • Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.