OR4D2

OR4D2
Identifiers
AliasesOR4D2, BC2009, OR17-24, olfactory receptor family 4 subfamily D member 2
External IDsMGI: 3030297 HomoloGene: 64870 GeneCards: OR4D2
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q22Start58,166,982 bp[1]
End58,171,411 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

124538

258408

Ensembl

ENSG00000255713

ENSMUSG00000093920

UniProt

P58180

Q5SW49

RefSeq (mRNA)

NM_001004707

NM_146413

RefSeq (protein)

NP_001004707

NP_666525

Location (UCSC)Chr 17: 58.17 – 58.17 MbChr 11: 87.89 – 87.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4D2 is a protein that in humans is encoded by the OR4D2 gene.[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000255713 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000093920 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR4D2 olfactory receptor, family 4, subfamily D, member 2".

Further reading

  • Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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