OR2H1

OR2H1
Identifiers
AliasesOR2H1, 6M1-16, HS6M1-16, OLFR42A-9004-14, OR2H6, OR2H8, OR6-2, dJ994E9.4, OLFR42A-9004.14/9026.2, olfactory receptor family 2 subfamily H member 1
External IDsMGI: 2177474 HomoloGene: 72346 GeneCards: OR2H1
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p22.1Start29,457,181 bp[1]
End29,464,328 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26716

258470

Ensembl

ENSMUSG00000095377

UniProt

Q9GZK4

Q7TRL3

RefSeq (mRNA)

NM_030883
NM_001318014
NM_001318022

NM_182714

RefSeq (protein)

NP_001304943
NP_001304951
NP_112145

NP_874373

Location (UCSC)Chr 6: 29.46 – 29.46 MbChr 17: 37.09 – 37.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 ENSG00000204688, ENSG00000224395, ENSG00000206471, ENSG00000229125, ENSG00000232984, ENSG00000229408, ENSG00000235132 GRCh38: Ensembl release 89: ENSG00000206516, ENSG00000204688, ENSG00000224395, ENSG00000206471, ENSG00000229125, ENSG00000232984, ENSG00000229408, ENSG00000235132 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000095377 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR2H1 olfactory receptor, family 2, subfamily H, member 1".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Santos PS, Kellermann T, Uchanska-Ziegler B, et al. (2010). "Genomic architecture of MHC-linked odorant receptor gene repertoires among 16 vertebrate species". Immunogenetics. 62 (9): 569–84. doi:10.1007/s00251-010-0468-6. PMID 20680261.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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