OR6C2

OR6C2
Identifiers
AliasesOR6C2, OR6C67, olfactory receptor family 6 subfamily C member 2
External IDsMGI: 3030625 HomoloGene: 71950 GeneCards: OR6C2
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q13.2Start55,444,069 bp[1]
End55,453,347 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

341416

258932

Ensembl

ENSG00000179695

ENSMUSG00000047626

UniProt

Q9NZP2

Q8VGJ0

RefSeq (mRNA)

NM_054105

NM_146930

RefSeq (protein)

NP_473446

NP_667141

Location (UCSC)Chr 12: 55.44 – 55.45 MbChr 10: 129.52 – 129.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 6C2 is a protein that in humans is encoded by the OR6C2 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000179695 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047626 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR6C2 olfactory receptor, family 6, subfamily C, member 2".

Further reading

  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
  • Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. doi:10.1038/nature04569. PMID 16541075.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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