OR2T4

OR2T4
Identifiers
AliasesOR2T4, OR1-60, OR2T4Q, olfactory receptor family 2 subfamily T member 4
External IDsMGI: 3030058 HomoloGene: 133015 GeneCards: OR2T4
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q44Start248,361,581 bp[1]
End248,362,627 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

127074

258198

Ensembl

ENSG00000196944
ENSG00000275617
ENSG00000274870

ENSMUSG00000059279

UniProt

Q8NH00

M9MMJ7

RefSeq (mRNA)

NM_001004696

NM_207695

RefSeq (protein)

NP_001004696

NP_997578

Location (UCSC)Chr 1: 248.36 – 248.36 MbChr 11: 58.57 – 58.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2T4 is a protein that in humans is encoded by the OR2T4 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 ENSG00000275617, ENSG00000274870 GRCh38: Ensembl release 89: ENSG00000196944, ENSG00000275617, ENSG00000274870 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059279 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR2T4 olfactory receptor, family 2, subfamily T, member 4".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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