OR4D1

OR4D1
Identifiers
AliasesOR4D1, OR17-23, OR4D3, OR4D4P, TPCR16, olfactory receptor family 4 subfamily D member 1
External IDsMGI: 3030298 HomoloGene: 44975 GeneCards: OR4D1
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q22Start58,148,449 bp[1]
End58,159,555 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26689

258407

Ensembl

ENSG00000141194

ENSMUSG00000060787

UniProt

Q15615

Q5SW48

RefSeq (mRNA)

NM_012374

NM_146412

RefSeq (protein)

NP_036506

NP_666524

Location (UCSC)Chr 17: 58.15 – 58.16 MbChr 11: 87.91 – 87.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4D1 is a protein that in humans is encoded by the OR4D1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141194 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060787 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
  6. 1 2 "Entrez Gene: OR4D1 olfactory receptor, family 4, subfamily D, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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