OR10A3

OR10A3
Identifiers
AliasesOR10A3, HSHTPCRX12, HTPCRX12, olfactory receptor family 10 subfamily A member 3
External IDsMGI: 3030352 HomoloGene: 133601 GeneCards: OR10A3
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start7,937,171 bp[1]
End7,941,708 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26496

258303

Ensembl

ENSG00000273953
ENSG00000170683
ENSG00000281680

ENSMUSG00000046431

UniProt

P58181

Q8VEW1

RefSeq (mRNA)

NM_001003745

NM_146306

RefSeq (protein)

NP_001003745

NP_666418

Location (UCSC)Chr 11: 7.94 – 7.94 MbChr 7: 108.88 – 108.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 10A3 is a protein that in humans is encoded by the OR10A3 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 ENSG00000170683, ENSG00000281680 GRCh38: Ensembl release 89: ENSG00000273953, ENSG00000170683, ENSG00000281680 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046431 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
  6. 1 2 "Entrez Gene: OR10A3 olfactory receptor, family 10, subfamily A, member 3".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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