OR2B2

OR2B2
Identifiers
AliasesOR2B2, OR2B2Q, OR2B9, OR6-1, dJ193B12.4, hs6M1-10, olfactory receptor family 2 subfamily B member 2
External IDsMGI: 3031194 HomoloGene: 11056 GeneCards: OR2B2
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6p22.1Start27,911,185 bp[1]
End27,912,396 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

81697

258536

Ensembl

ENSG00000168131

ENSMUSG00000108534

UniProt

Q9GZK3

n/a

RefSeq (mRNA)

NM_033057

NM_146543

RefSeq (protein)

NP_149046

n/a

Location (UCSC)Chr 6: 27.91 – 27.91 MbChr 13: 21.67 – 21.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2B2 is a protein that in humans is encoded by the OR2B2 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000168131 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000108534 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR2B2 olfactory receptor, family 2, subfamily B, member 2".

Further reading

  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.