OR13H1

OR13H1
Identifiers
AliasesOR13H1, ORX1, olfactory receptor family 13 subfamily H member 1
External IDsHomoloGene: 105272 GeneCards: OR13H1
Gene location (Human)
Chr.X chromosome (human)[1]
BandXq26.2Start131,543,976 bp[1]
End131,545,056 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

347468

n/a

Ensembl

ENSG00000171054

n/a

UniProt

Q8NG92

n/a

RefSeq (mRNA)

NM_001004486

n/a

RefSeq (protein)

NP_001004486

n/a

Location (UCSC)Chr X: 131.54 – 131.55 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 13H1 is a protein that in humans is encoded by the OR13H1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171054 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. 1 2 "Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1".

Further reading

  • Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
  • Buck L, Axel R (1991). "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition". Cell. 65 (1): 175–87. doi:10.1016/0092-8674(91)90418-X. PMID 1840504.
  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome". Biochem. Biophys. Res. Commun. 237 (2): 283–7. doi:10.1006/bbrc.1997.7043. PMID 9268701.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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