OR2D2

OR2D2
Identifiers
AliasesOR2D2, OR11-610, OR2D1, hg27, olfactory receptor family 2 subfamily D member 2
External IDsMGI: 3647188 HomoloGene: 81541 GeneCards: OR2D2
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start6,891,490 bp[1]
End6,892,599 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

120776

384732

Ensembl

ENSG00000166368

ENSMUSG00000062987

UniProt

Q9H210

E9Q725

RefSeq (mRNA)

NM_003700

NM_001162940

RefSeq (protein)

NP_003691

NP_001156412

Location (UCSC)Chr 11: 6.89 – 6.89 MbChr 7: 107.1 – 107.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2D2 is a protein that in humans is encoded by the OR2D2 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000166368 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062987 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
  6. 1 2 "Entrez Gene: OR2D2 olfactory receptor, family 2, subfamily D, member 2".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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