OR2AE1

OR2AE1
Identifiers
AliasesOR2AE1, OR2AE2, olfactory receptor family 2 subfamily AE member 1
External IDsHomoloGene: 128272 GeneCards: OR2AE1
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q22.1Start99,875,987 bp[1]
End99,877,057 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

81392

n/a

Ensembl

ENSG00000244623

n/a

UniProt

Q8NHA4

n/a

RefSeq (mRNA)

NM_001005276

n/a

RefSeq (protein)

NP_001005276

n/a

Location (UCSC)Chr 7: 99.88 – 99.88 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000244623 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. 1 2 "Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1".

Further reading

  • "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
  • Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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