OR4L1

OR4L1
Identifiers
AliasesOR4L1, OR14-28, OR4L2P, olfactory receptor family 4 subfamily L member 1
External IDsMGI: 3030558 HomoloGene: 71986 GeneCards: OR4L1
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q11.2Start20,060,045 bp[1]
End20,060,983 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

122742

258485

Ensembl

ENSG00000176246

ENSMUSG00000096254

UniProt

Q8NH43

K7N5X7

RefSeq (mRNA)

NM_001004717

NM_146492

RefSeq (protein)

NP_001004717

NP_666703

Location (UCSC)Chr 14: 20.06 – 20.06 MbChr 14: 49.96 – 49.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4L1 is a protein that in humans is encoded by the OR4L1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000176246 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000096254 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: OR4L1 olfactory receptor, family 4, subfamily L, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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