Monoamine receptor

A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine structure. The monoamine receptors are almost all G protein-coupled receptors, with the serotonin 5-HT3 receptor being a notable exception as a ligand-gated ion channel.[1] Monoamine receptors are the biological targets of many drugs; such drugs may be referred to as "monoaminergic".

The serotonin 5-HT1B receptor as an example of a monoamine receptor.[1] Its crystallographic structure in ribbon representation.

List of receptors

Monoamine receptors include the following classes:

References

  1. Martin, Andres; Scahill, Lawrence; Kratochvil, Christopher (14 December 2010). Pediatric Psychopharmacology. Oxford University Press. p. 31. ISBN 9780199842667. Retrieved 27 January 2017. The 5-HT3 receptor is the only monoamine receptor coupled to an ion channel, probably a Ca2+ channel.



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